At TenAces Biosciences, we aim to improve patients’ lives
by developing rationally designed molecular glue therapeutics.

About us

TenAces Biosciences is a biopharmaceutical company focused on the development of molecular glue therapeutics. Our molecular glues are small molecules that can induce or stabilize the interaction between an E3 ligase and a target protein. This enhanced binding accelerates the tagging with ubiquitin, and subsequent removal of the target protein by the proteasome.

Our discovery engine can predict the most suitable E3 ligases for highly selective and tissue-specific targeting, and compounds to stabilize the interactive surface with the target protein. This approach, based on machine learning, 3D modeling and virtual compound screening, allows for the development of rationally designed molecular glues for a wide range of diseases.

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